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KMID : 0385919950060010122
Journal of the Korean Society of Emergency Medicine
1995 Volume.6 No. 1 p.122 ~ p.131
CLINICAL SIGNFIICANCE OF QUALITATIVE TEST FOR DETECTION OF URINARY PARAQUAT BY SODIUM DITHIONITE
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Abstract
Background:
@EN Mortality from paraquat intoxication depends upon plasma paraquat concentration. To know the severity of paraquat intoxication is important for directing therapeutic modality and predicting prognosis. Sodium dithionite test for urinary
paraquat
provides an easy and simple method to determine the severity of paraquat intoxication in emergency department.
@ES purpose:
@EN To determine whether the result urinary paraquat test by sodium dithionite can predict outcome in patients with paraquat intoxication in emergency department.
@ES Subjects:
@EN 48 patients(male 31, female 17, mean age 37 years) who had exposure to paraquat and presented within 24 hours after exopsure.
@ES Results:
@EN Thrty five patients were positive in paraquat urine test and thirteen patients were negative. Clinical manifestations were more severe in positive patients than in negatives. Complication was much more in positive than in negatives. 28 of 35
patients(80%) in positives and 2 of 13 patients(15%0 in negatives died.
@ES Conclusion:
@EN Positive test for urinary paraquat is associated with high mortality and morbidity from paraquat intoxication, and qualitative test for urinary paraquat by sodium dithionite is an useful method to determine the severity of paraquat
intoxication
in
emergency department.
KEYWORD
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